Cells, Free Full-Text
Por um escritor misterioso
Descrição
Immunometabolism is an emerging discipline in cancer immunotherapy. Tumor tissues are heterogeneous and influenced by metabolic reprogramming of the tumor immune microenvironment (TIME). In the TIME, multiple cell types interact, and the tumor and immune cells compete for limited nutrients, resulting in altered anticancer immunity. Therefore, metabolic reprogramming of individual cell types may influence the outcomes of immunotherapy. Understanding the metabolic competition for access to limited nutrients between tumor cells and immune cells could reveal the breadth and complexity of the TIME and aid in developing novel therapeutic approaches for cancer. In this review, we highlight that, when cells compete for nutrients, the prevailing cell type gains certain advantages over other cell types; for instance, if tumor cells prevail against immune cells for nutrients, the former gains immune resistance. Thus, a strategy is needed to selectively suppress such resistant tumor cells. Although challenging, the concept of cell type-specific metabolic pathway inhibition is a potent new strategy in anticancer immunotherapy.
JCM, Free Full-Text
Streptomyces cell-free systems for natural product discovery and engineering - ScienceDirect
STEM CELLS: Vol 35, No 5
PDF) Comparative separation methods and biological characteristics of human placental and umbilical cord mesenchymal stem cells in serum-free culture conditions
Cell Circuits and Complex Tissues
Cancer type classification using plasma cell-free RNAs derived from human and microbes
The emerging impact of cell-free chemical biosynthesis - ScienceDirect
Remote immune processes revealed by immune-derived circulating cell-free DNA
Cell-Free Synthetic Biology for Pathway Prototyping - ScienceDirect
Cells, Free Full-Text
Scheme of cell free cloning using DMF. ( A ) The full length construct
de
por adulto (o preço varia de acordo com o tamanho do grupo)
