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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered

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Researchers from the group Mitochondrial regulation of cell death and steatohepatitis have revealed a new role for acid ceramidase (ACDase) in experimental models and in patients with NPC through the regulation of STARD1 and its impact on mitochondrial function.
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
STARD1 and NPC1 expression as pathological markers associated with astrogliosis in post-mortem brains from patients with Alzheimer's disease and Down syndrome
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
STARD1 Functions in Mitochondrial Cholesterol Metabolism and Nascent HDL Formation. Gene Expression and Molecular mRNA Imaging Show Novel Splicing and a 1:1 Mitochondrial Association. - Abstract - Europe PMC
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
NPC1 enables cholesterol mobilization during long‐term potentiation that can be restored in Niemann–Pick disease type C by CYP46A1 activation
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
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A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Cells, Free Full-Text
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Molecular mechanism(s) of neurodegeneration in Niemann-Pick type C disease - Ruđer Bošković Institute
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Niemann–Pick type C disease: cellular pathology and pharmacotherapy - Wheeler - 2020 - Journal of Neurochemistry - Wiley Online Library
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
IJMS, Free Full-Text
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Animals, Free Full-Text
A new regulatory mechanism of STARD1 in Niemann-Pick disease type C (NPC), discovered
Mitochondrial dysfunction in fibroblasts derived from patients with Niemann-Pick type C disease - ScienceDirect
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